8-12 July 2019
Cité des Congrès
Europe/Paris timezone

Linking lineage and population observables in biological branching processes

9 Jul 2019, 09:00
15m
Salle J (Cité des Congrès)

Salle J

Cité des Congrès

Speaker

Dr David LACOSTE (Laboratoire Gulliver, ESPCI)

Description

Using a population dynamics inspired by an ensemble of growing cells, a set of fluctuation theorems linking observables measured at the lineage and population levels are derived [1]. One of these relations implies specific inequalities comparing the population doubling time with the mean generation time at the lineage or population levels. While these inequalities have been derived before for age controlled models with negligible mother-daughter correlations, we show that they also hold for a broad class of size-controlled models. We discuss the implications of this result for the interpretation of a recent experiment in which the growth of bacteria strains has been probed at the single cell level.

[1] Linking lineage and population observables in biological branching processes,
https://www.biorxiv.org/content/10.1101/527291v1

Choix de session parallèle 2.4 Fluctuation et biologie

Primary author

Reinaldo Garcia-Garcia

Co-authors

Arthur Genthon Dr David LACOSTE (Laboratoire Gulliver, ESPCI)

Presentation Materials