Orateur
Dr
Bianca Sclavi
(LBPA, UMR 8113)
Description
The bacterial genome is not uniformly organized, with binding sites for
nucleoid associated proteins and topoisomerases found in clusters or in a
gradient from the origin to the terminus, in addition the position of
several key genes regulating cellular growth and adaptation is conserved
when comparing the known gamma proteobacterial genomes. We thus asked
whether the position of a gene can influece its expression and its
regulation in response to stress. We have used a fluorescent
protein reporter construct at six different positions along the chromosome
in order to address this question.
