Cold dark matter is known to structure on scales much smaller than typical galaxies. This structuring translates into a large population of subhalos in galactic halos that impact indirect dark matter searches by boosting the annihilation signal (gamma rays, antimatter cosmic rays). I will present a model of the Galactic subhalo population fully consistent with dynamical constraints. The mass, concentration and spatial distributions of these objects are predicted from first principles and inherit from cosmological properties. I will detail the impact of this subhalo population on indirect searches with gamma rays and cosmic-ray antiprotons.