Assemblée Générale 2023 du GdR Mi2B

Session

Pôle Effets des Irradiations sur le Vivant

6 oct. 2023, 09:00

Bâtiment CREATIF (LP2IB)

Présidents de session

Pôle Effets des Irradiations sur le Vivant

• HERVE SEZNEC (CENBG, CNRS/IN2P3)
• Michael Beuve (Université Lyon 1)
• Mathilde Badoual (Université Paris 7)
• Patrick VERNET (LPC, Université Clermont Auvergne)

Pôle Effets des Irradiations sur le Vivant

• Patrick VERNET (LPC, Université Clermont Auvergne)
• Hervé Seznec
• Mathilde Badoual (Université Paris 7)
• Michaël Beuve

46. Nouvelles du pôle

Hervé Seznec, Mathilde Badoual, Michaël Beuve, Patrick Vernet

06/10/2023 09:00

42. Hadrontherapy to target glioblastoma stem cells to overcome radioresistance

Juliette AURY-LANDAS

06/10/2023 09:18

Aury-Landas J1, Pérès EA1, Pasquet N1, Helaine C1, Lebhertz D, Taylor J1, Toutain J1, Bernaudin M1 and Valable S1
1 Université de Caen Normandie, CNRS, Normandie Université, ISTCT, UMR6030, GIP Cyceron, F-14000 Caen, France
2 Centre de Lutte Contre le Cancer François Baclesse, F-14000 Caen, France

Glioblastoma (GBM) are brain tumors resistant to conventional therapies, in particular to...

43. Characterizing the Time-Dependent Response of a Population of Gliomas to Single-Dose Radiation: Comparison of a Mathematical Model With Experiments

Marianne Billoir

06/10/2023 09:36

Gliomas are a type of brain tumor distinguished by their highly invasive cells exhibiting the capacity to migrate considerable distances while remaining below the detection threshold of MRI scans. This inherent invasiveness often leads to unavoidable tumor reappearance post-treatment. Radiotherapy stands as a crucial cornerstone of their therapeutic strategy, entailing the delivery of...

44. La radiolyse pour la santé : quels intérêts ?

Emeline Craff

06/10/2023 09:54

45. In situ study of proton-induced DNA fragmentation using fluorescence microscopy and single particle tracking.

Rémy Lienard

06/10/2023 10:12

I study by an in situ approach the dynamic and statistical properties of the radiation-induced fragmentation of T4 bacteriophage virus DNA molecules in solution. In particular, I couples machine learning and python algorithm of particle tracking in order to determine the fragmentation probabilities of DNA molecules when they are submitted to ionizing radiation.

47. Ours brun : un modèle innovant dans l'étude de la radioprotection

Jade Sutter (LPC)

06/10/2023 10:55

48. Radiorésistance tumorale et thérapies innovantes : Développement de nanoparticules d’or fonctionnalisées et caractérisation de leurs propriétés radio-biologiques sur un modèle cellulaire de tumeur prostatique.

Thibaut Tabanou (LPC)

06/10/2023 11:13

32. Etude d'impact de la distribution intracellulaire de radionucléides en radiothérapie interne vectorisée alpha, par une modélisation Monte-Carlo biophysique en géométrie 3D multicellulaire

Victor Levrague (LPSC)

06/10/2023 11:31

49. Ionising radiation effects on DNA using Geant4-DNA Monte Carlo simulations

Sara Zein

Monte Carlo track structure codes usually simulate particle tracks in liquid water since it makes up to 70% of living cells. Since DNA is considered the most radio sensitive target within eukaryotic cells simulating particle tracks within the DNA molecule is of high interest [1]. We implemented physics models of electrons in the 4 DNA bases as well as the sugar and the phosphate group on DNA...