Advancing radiation-induced oral mucositis mitigation in proton therapy for head and neck cancer patients

par Laurine Schnelzauer (University of Miami)

vendredi 18 déc. 2026, 14:00 → 16:00 Europe/Paris

Amphi Grunewald (Bat 25)

Proton therapy for cancer treatment offers the potential to reduce radiation exposure to healthy tissues compared with conventional radiotherapy, while increasing dose conformality to the tumor. However, patients still experience significant treatment-related side effects, highlighting the limitations of current treatment planning. In this talk, I will explore how machine learning can help address this challenge by integrating clinical, dosimetric, and radiation quality data to predict oral mucositis in head and neck cancer treatment. I will show how machine learning, combined with microdosimetry and Monte Carlo simulations, can improve toxicity prediction and guide the development of more effective treatment-planning strategies, paving the way toward safer proton therapy.